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diagnosis ana antinuclear patterns cytoplasmic management nuclear biliary cardiology cholangitis cirrhosis fungal hepatology infections infectiousdiseases mycoses palpitations pbc primary prs
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody ... Testing - Nuclear ... #Testing #Nuclear ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
pericarditis • Hepatic: PBC ... calcinosis • Pulmonary ... Scleroderma #SSc #rheumatology ... signs #symptoms #testing ... #workup
Antinuclear Antibody Testing Cytoplasmic Patterns Reticular/AMA: • PBC, SSc, PBC/SSc OS, PBC/SjS OS • AMA Speckled: •
Reticular/AMA: • PBC ... , SSc, PBC/SSc OS ... , PBC/SjS OS • ... #Patterns #differential ... #diagnosis #rheumatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
) - Summary PBC ... Proximal limb muscle wasting ... bile ducts Differential ... cholestasis, Primary sclerosis ... cholangitis #diagnosis #workup
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
Testing - Nuclear ... pattern: • SSc, PBC ... dots pattern: • PBC ... #Patterns #differential ... #diagnosis #rheumatology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Inflammatory eye disease: scleritis ... mononeuritis multiplex WORKUP ... Auto-antibodies: ANCA antibody ... , Anti-GBM antibody ... Renal #Syndromes #differential
Palpitations - Differential Diagnosis Framework What? • It is an unpleasant awareness or sensation that the heart is
Palpitations - Differential ... Limited laboratory testing ... Pheochromocytoma • Pulmonary ... palpitations: PVC ... Palpitations #Cardiology #Differential
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
symptoms • Rheumatologic ... Pericarditis • Sclerosing ... aches, joint pain, chest ... Urinary antigen testing ... transplantation • MCC
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