135 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody Testing ... pattern: - PBC ... , SSc, PBC/SSc OS ... , PBC/SjS OS ... SjS, SLE, RA, PBC
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Ducts - PBC ... , PSC, Alcoholic ... Hep, Drugs, Infection ... Biliary stricture, PSC ... Algorithm #diagnosis #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... Parenchyma • Infectious ... Malignancy, 1° PBC ... , 1° PSC, Cystic ... Acute #algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
) - Summary PBC ... 30-65 years PBC ... intralobular bile ducts causes ... Proximal limb muscle wasting ... fungal, viral infections
Causes of Fat Malabsorption - Differential Diagnosis
Biliary Duct Obstruction
 • Autoimmune— PBC, PSC
 • Infection— liver
Causes of Fat Malabsorption ... • Autoimmune— PBC ... , PSCInfection ... bowel resection Infectious ... Differential #Diagnosis #Causes
Premature Ventricular Complexes (PVC's) - Summary Framework

Why PVCs?  Can be the first manifestation of cardiac
Presyncope PVC ... Diagnosis: • PAC ... A PAC also has a ... than a PVC ... more intensive treatment
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
procedures - Infection ... for decreased PLT ... smear, HIV/HCV testing ... or if a primary hematologic ... #Workup #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... drug reaction, infection ... Strongyloides infection ... glucocorticoid treatment ... Differential #diagnosis #hematology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Intestine - Other causes ... biliary Cholangitis (PBC ... Infiltrative diseases - PSC ... Diagnosis #Algorithm #hepatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... Myelofibrosis Infectious ... effect following treatment ... Diagnosis #Algorithm #Causes ... #Hematology