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rheumatology disease causes hematology summary syndrome acidosis activation behcet classification coagulation dic differential disseminated elevation fungal hemophagocytic hlh infections infectiousdiseases
Septic Arthritis - Diagnosis and Management Summary Clinical Exam: hot, swollen, pain with passive AND active ROM
Septic Arthritis ... Clinical Exam: ... arthritis diagnosis ... 90% sensitive in pediatrics ... #Arthritis #Diagnosis
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... Fever, Arthralgia/arthritis ... splenomegaly • Hepatic ... Prunelle Getten #AdultOnset ... #management #treatment
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... erythema nodosum (septal ... Behcet syndrome (Clinical ... , AS Treatment: ... #management #signs
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
history of trauma, sepsis ... organ damage Clinical ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Cytopenia +++ (Plt ... Unknown cause Treatment ... #management #treatment
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Fever is the main clinical ... brucellosis) • Sepsis ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
www.ncbi.nlm.nih.gov/pmc ... shock/hypoxemia/Sepsis ... / hypoxemia -> focus ... before beginning treatment ... syndrome - Sepsis
Legionnaires' Disease Clinical features: • Gl- nausea, vomiting, diarrhea • Hyponatremia • Elevated transaminases • CRP >100
Legionnaires' Disease Clinical ... respond to B-Lactams Treatment ... arthritis, OM, ... Legionnaires #Disease #diagnosis ... #management
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
has five major clinical ... fungal stain of clinical ... • Meningitis, septic ... arthritis, and ... #Management #Infections
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