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hematology hellp leukemia management obstetrics pregnancy table thrombocytopenia ttphus anemia aplastic chronic cll differential differentiation lymphocytic mds monoclonal myelodysplasia myelodysplastic
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
TTP/HUS, HELLP Syndrome ... of Pregnancy (AFLP ... ) Three syndromes ... #diagnosis #table ... #comparison
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... develop leukostasis syndrome ... smear: Blasts APML ... • Tumor lysis syndrome ... #Oncology #Diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Differentiation #Syndrome ... #APML #diagnosis ... #management #hematology ... #oncology
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
Pregnancy Three syndromes ... TTPHUS #HELLP #AFLP ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... • ↓ WBC • ↓ PLT ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
capillary leak syndrome ... Organomegaly+↑RBC/plt ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... • Richter’s Syndrome ... Transform to DLBCL, PML ... #workup #oncology ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... transformation to AML ... progression to AML ... #diagnosis #hematology ... #oncology
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