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diagnosis differential algorithm hemolytic arterial clinical dyspnea embolism extravascular gangrenosum hemolysis intravascular leukemia nonpalpable oncology palpable pathophysiology photo pulmonary purpura
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
: - Thrombocytopenia ... - Hemolytic anemia ... deficiencies - PNH ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Megakaryopoiesis • Aplastic Anemia ... HUS • DIC • Vasculitis ... Diagnosis #Algorithm #Causes ... #Hematology
Pyoderma Gangrenosum: Autoimmune disorder resulting in a vasculitis which causes slowly progressive ulceration of the skin.
resulting in a vasculitis ... which causes slowly ... Goldberg, M.D. - UCSD ... Clinical #Photo #Dermatology ... #SkinRash #Pyoderma
Skin Ulcers by Etiology - Differential Diagnosis Algorithm Physical: • Trauma • Pressure • Radiation Vascular: • Arterial
insufficiency • Vasculitis ... • Bleomycin Hematologic ... • Sickle Cell Anemia ... Ulcers #ulcerative #skinrash ... #dermatology #Differential
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
Cardiovascular Causes ... - Water - Pus ... Pulmonary HTN - Vasculitis ... Transverse myelitis • Hematology ... : - Anemia •
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... platelet decrease - PNH ... Schistocytes, thrombocytopenia ... cardiac valve, vasculitis ... Algorithm #workup #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... microangiopathy: Thrombotic thrombocytopenic ... hemoglobinuria (PNH ... differential #diagnosis #hematology ... #anemia
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Heparin-induced thrombocytopenia ... coagulation and other causes ... - COVID-19 - PNH ... - Vasculitis ... pathophysiology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... count ↑ PLT • ↑ PBS ... - infiltrates (anemia ... , thrombocytopenia ... #Leukemia #Hematology
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