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diagnosis algorithm management anemia hemolysis liver ascites disease extravascular hepatitis hepatopulmonary intravascular oncology pulmonary rheumatology aflp agglutinin anticoagulation arterial bilirubin
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... uremic syndrome ... hemoglobinuria (PNH ... #differential # ... diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... - Differential ... • PCH • PNH ... Extravascular #Differential ... #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
- Differential ... Congestive • Cirrhosis ... Serum Sickness Hemolytic ... Spleen #Enlarged #Differential ... #Hematology
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Etiologies of Cirrhosis ... disease (Budd-Chiari syndrome ... #Diagnosis #Differential ... #Hepatology #Cirrhosis ... #Causes
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 Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
Jaundice - Differential ... Production • Hemolysis ... • Gilbert's Syndrome ... Diagnosis #Algorithm #Causes ... #Hepatology #bilirubinemia
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... >10 mmHg - clinically ... and hepatorenal syndrome ... Clues to non-cirrhotic ... #hepatology
Causes of Portal Hypertension According to Site of Vascular Obstruction 1) Prehepatic pre-sinusoidal: Portal vein thrombosis due
Causes of Portal ... post-sinusoidal: Budd-Chiari syndrome ... portalhypertension #phtn #differential ... #diagnosis #causes ... #hepatology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... - Differential ... iron deficiency, hemolysis ... Myelodysplastic syndrome ... #hematology #secondary
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Hepatomegaly - Differential ... • Budd-Chiari Syndrome ... Primary Biliary Cirrhosis ... Diagnosis #Algorithm #Causes ... #Hepatology
Causes of Pleural Effusion - Differential Diagnosis Algorithm Transudate - Hydrostatic • Congestive heart failure • Constrictive
Causes of Pleural ... Effusion - Differential ... - Oncotic • Cirrhosis ... Diagnosis #Algorithm #Hepatology ... #causes
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