9 results
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm

1. Definition: T.bili elevation + >20% conjugated
2. Obtain RUQ
Diagnosis Algorithm ... - rule out non-ICU ... vs ICU causes ... MRCP, ERCP, liver ... gastroenterology #hepatology
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
- NEJM 1999 - ICU ... FOCUS - NEJM 2011 ... Blood saves lives ... unnecessary and cause ... Transfusion #Thresholds #Hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... infiltration) Differential ... Maternal Support - Critical ... #Pregnancy #hepatology ... obgyn #diagnosis #management
Portal venous gas on hepatic ultrasound: A concerning finding in the critically ill patient that should
reflection on the differential ... variety of other causes ... venousgas #ultrasound #hepatology ... #liver #pocus # ... clinical #air
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... DIC • Severe Liver ... Treat primary cause ... #treatment #management ... #hematology
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
fatigue despite clinical ... Receptor (sTfR) to differentiate ... and/or stress • Pts ... /other causes • ... #diagnosis #management
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... Differential Diagnosis ... Clinical • Under-recognized ... • Minority of Pts ... Avoid ARBs • ICD
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
JVD, Orthopnea/PND ... the determined cause ... #diagnosis #differential ... #algorithm #management ... #criticalcare #icu
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... salivary ducts Clinical ... vasculitis: 10%-16% Liver ... Nephrogenic DI Hematologic ... #Diagnosis #Management