55 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... -> AML: Blast crises ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Hematology #Oncology
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
- Tamponade Pulmonary ... - Water - Pus ... Hepatopulmonary syndrome ... Transverse myelitis • Hematology ... #pulmonary
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
neutrophil in a case ... acute myeloid leukemia ... neutrophils #AML #Clinical ... #Hematology #Pathology
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia ... features in most cases ... promyelocytic #leukemia ... APML #Pathology #Hematology ... #Clinical #Smear
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Leukemia, Tumour ... Non-lmmune: • HELLP Syndrome ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Causes of Thrombocytosis ... Myelodysplastic syndrome ... Chronic myeloid leukemia ... Differential #Diagnosis #Causes ... #hematology #secondary
Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... Acute Eosinophilic Leukemia ... Hypereosinophilic Syndrome ... Chronic Eosinophilic Leukemia ... #hematology
Recurrent / Breakthrough DVT During Anticoagulation

Subtherapeutic Anticoagulation
Hypercoagulable State 
 - Antithrombin deficiency 
 - Hypercoagulability ot
APLS - MPN/PNH ... Structural - Pelvic masses ... - May-Thurner syndrome ... anticoagulation #hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Script Signs and symptoms ... to MDS or acute leukemia ... • Associated PNH ... management #treatment #hematology
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm
Relative - Normal RBC Mass / Decreased Plasma Volume
Causes of Polycythemia ... Splenomegaly, Increased PMNs ... Cyanosis without Pulmonary ... Chronic Chest Symptoms ... #Hematology