11 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... autoantibodies that will cause ... permeability Diagnosis ... #neurology #rheumatology ... #management #treatment
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... disorders (Systemic lupus ... syndrome, Myasthenia gravis ... Manifestations #diagnosis ... #neurology #symptoms
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Clinical Picture ... myasthenia Diagnosis ... immunologic assay - MuSK ... #diagnosis #management ... #neurology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
et diutinum Neurologic ... Amyloidosis (CVS+PNS ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
Myasthenia Gravis ... : • Based on clinical ... More likely to cause ... #diagnosis #management ... #neurology #treatment
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Systemic lupus ... nervous system (CNS ... SJIA], systemic lupus ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... : • A clinical ... out other causes ... #diagnosis #management ... #Dermatology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... Transverse Myelitis - Clinical ... bouts of HTN Diagnostic ... • Infectious causes ... #management #neurology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... salivary ducts Clinical ... Nephrogenic DI Hematologic ... phenomenon (16%) MSK ... #Diagnosis #Management