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diagnosis management rheumatology myelodysplastic neurology syndromes activation anemia antinxp2 antinxp2dm aplastic bee cerebritis cns dermatomyositis differential erythematosus lupus macrophage mas
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... #MDS #Diagnosis ... #Management #treatment ... #hematology #oncology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Clinical Presentation ... nervous system (CNS ... Petechial or purpuric rash ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
- Rash: multiple ... Causes: - Idiopathic ... Treatment: - Systemic ... #diagnosis #dermatology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... and petechiae Causes ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... autoantibodies that will cause ... Maheswaranathan, MD ... #neurology #rheumatology
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
Non-inflammatory Causes ... nervous system (CNS ... diagnosis and treatment ... MRI lesions and clinical ... consistent with MS
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
(MDS) What? ... Out Secondary Causes ... factor (GCSF) treatments ... #diagnosis #hematology ... #oncology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... Rheumatic pain Clinical ... Rule out other causes ... and lower jaw Treatment ... diagnosis #management #Dermatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... salivary ducts Clinical ... Nephrogenic DI Hematologic ... phenomenon (16%) MSK ... Adenocarcinoma Treatment
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
subcutaneous edema Pts ... auricular papules Clinical ... Muscle atrophy may cause ... positive patients Treatment ... #dermatology
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