10 results
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework

STRUCTURAL:
 - PFO: paradoxical emboli
 - Popliteal
Causes of Arterial ... artery aneurysm: Causes ... APLS:PLT ↓ HEMATOLOGIC ... neoplasms - PNH ... Diagnosis #clots #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Hematological: - HIT, PNH ... considered in all cases ... coagulation and other causes ... - COVID-19 - PNH ... pathophysiology #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
deficiencies - PNH ... gangrenosum • Bacterial ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Scleroderma • Dermatomyositis ... usually painful • Bacterial ... Systemic #Secondary #dermatology ... Diagnosis #Algorithm #causes
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... blood test • Serology ... Diagnosis #Algorithm #Causes ... #dermatology #physicalexam
Dermatomyositis with heliotrope rash, shawl sign, and Gottron's papules

A middle-aged man describes progressive difficulty combing his
Dermatomyositis ... describes progressive difficulty ... out this is a case ... of dermatomyositis ... GottronsPapules #dermatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Causes: - Idiopathic ... , breast CA - Hematologic ... multiforme - Dermatomyositis ... Acral erythema - Bacterial ... Syndrome #diagnosis #dermatology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
membrane into the CNS ... respiratory failure • Neurologic ... Waddling gait - Difficulty ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
affects the skin, neurologic ... syndrome • Coronary arteries ... cognitive impairment, neurologic ... tract, and often causes ... Thrombosis and arterial
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
Anti-NXP-2 Dermatomyositis ... subcutaneous edema Pts ... Muscle atrophy may cause ... diagnosis #management #rheumatology ... #dermatology