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diagnosis rheumatology dermatology oncology algorithm clinical extravascular hemolysis intravascular photo syndrome aids aplastic arteritis autoimmune canimorsus capnocytophaga classification cutaneous erythematosus
Transplant Infections Timeline Pre-transplant: • Common bacteria (endogenous): Staphylococci (skin), Gram-negative bacilli (gut) • Viruses: HSV (reactivation) Engraftment:
Transplant Infections ... Clostridioides difficile ... #Timeline #differential ... #diagnosis #causes ... #infectiousdiseases
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... purple, hemorrhagic skin ... - Hemolytic anemia ... SLE) - Viral infections ... deficiencies - PNH
Skin Ulcers by Etiology - Differential Diagnosis Algorithm Physical: • Trauma • Pressure • Radiation Vascular: • Arterial
Skin Ulcers by Etiology ... • Bleomycin Hematologic ... • Sickle Cell Anemia ... Cryoglobulinemia Infectious ... Diagnosis #Algorithm #causes
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... hemoglobinuria (PNH ... #differential # ... diagnosis #hematology ... #anemia
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... circulation - Infections ... • PCH • PNH ... immune-complex hemolytic anemia ... #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Headaches • Pale skin ... color • Difficulty ... and petechiae Causes ... #oncology #hematology ... #diagnosis #management
Capnocytophaga Canimorsus Skin Rash 40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
Bandemia, AKI. ... dogs & latter can cause ... gram-negative bacillus cause ... the organism is difficult ... #Rash #dermatology
Waterborne Infections - Differential Diagnosis Framework Infections that can be acquired from fresh water, brackish water, sea
- Differential ... Blooms (HABs) Skin ... dermatitidis CNS ... #Differential # ... Diagnosis #InfectiousDiseases
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... -> AML: Blast crises ... - infiltrates (anemia ... CLL -> Invade Skin ... #Leukemia #Hematology
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Hematologic malignancy ... Bone Marrow - Anemia ... #differential # ... diagnosis #infectiousdiseases
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