59 results
diagnosis management algorithm rheumatology neurology radiology anemia workup cardiology hypertension msk treatment classification hemolysis oncology brain cardiomyopathy cirrhosis cns dermatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... hemoglobinuria (PNH ... lymphoproliferative disorders ... #differential # ... diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... - Differential ... • PCH • PNH ... Extravascular #Differential ... #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... DIC/TTP/HUS - Hemolytic ... Kasabach-Merritt syndrome ... deficiencies - PNH ... #Diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
- Differential ... iron deficiency, hemolysis ... Chronic inflammatory disorders ... Myelodysplastic syndrome ... #hematology #secondary
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
- Differential ... Myeloproliferative disorders ... Serum Sickness Hemolytic ... Spleen #Enlarged #Differential ... #Hematology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
Inherited Non-hemolytic ... without evidence of hemolysis ... as jaundice on clinical ... and stress may cause ... Congenital #bilirubin #hepatology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... platelet decrease - PNH ... Consider RBC membrane disorder ... #Anemia #Differential ... Algorithm #workup #hematology
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
Jaundice - Differential ... Production • Hemolysis ... • Gilbert's Syndrome ... Diagnosis #Algorithm #Causes ... #Hepatology #bilirubinemia
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
lymphoproliferative disorder ... Cold Agglutinin Syndrome ... Viral Infection Clinical ... ) Differential ... #anemia #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Algorithm Consumption Disorders ... PNH 2. ... HLH syndrome 5. ... Eating disorders ... Diagnosis #Algorithm #Hematology
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