53 results
diagnosis differential management algorithm oncology dermatology smear thrombocytosis classification hemolysis intravascular pathology pathophysiology reactions rheumatology treatment workup aplastic atlas extravascular
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... • PCH • PNH ... anemia • ... Acute HTR - Mechanical ... #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Normal RBCs • Acute ... Bleed • Hemolysis ... Microangiopathic Hemolytic ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... anemia): ... hemoglobinuria (PNH ... differential #diagnosis #hematology ... #anemia
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Peripheral Blood ... Microangiopathic hemolytic ... #Peripheral #Blood ... Smear #Analysis #hematology ... interpretation #clinical
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Chronic Myelogenous Leukemia ... Infectious: • Acute ... Iron deficiency anemia ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Thrombocytosis): • Acute ... malignancies • Anemia ... iron deficiency, hemolysis ... Chronic myeloid leukemia ... #hematology #secondary
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
Acute promyelocytic ... leukemia (blood ... features in most cases ... APML #Pathology #Hematology ... #Clinical #Smear
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Reactive: • Anemia ... /blood loss (Fe ... Chronic Myeloid Leukemia ... Differential #Diagnosis #causes ... #Platelets #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... the peripheral blood ... -> AML: Blast crises ... - infiltrates (anemia ... #Hematology #Oncology
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... microangiopathic hemolytic ... anemia. ... DIC is a clinical ... #anemia #Hematology
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