14 results
diagnosis differential algorithm coagulation management abnormal prolonged pt vte cancer doac malignancy pathophysiology ptt treatment anticoagulant apixaban arterial bleeding breakthrough
How to Evaluate an Abnormal APTT Step 1: Is the PT or APTT Artifactually Prolonged? Step 2: Is
Evaluate an Abnormal APTT ... : Is the PT or APTT ... K Antagonists, Heparin ... to identify the cause ... prolonged #diagnosis #hematology
Recurrent / Breakthrough DVT During Anticoagulation Subtherapeutic Anticoagulation Hypercoagulable State - Antithrombin deficiency - Hypercoagulability ot
Breakthrough DVT During Anticoagulation ... Subtherapeutic Anticoagulation ... APLS - MPN/PNH ... Structural - Pelvic masses ... #hematology #differential
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Treat primary cause ... 100mg/dL) - Heparin ... INR < 2.3 - APTT ... Coagulation #diagnosis #causes ... treatment #management #hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Prolonged PT and aPTT ... the PT and the aPTT ... (e.g. heparin contamination ... thrombin inhibitors, heparin ... #differential #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... unfractionated heparin ... Pre-analytical cause ... e.g. heparin ... #differential #hematology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis. Currently, edoxaban and rivaroxaban are the only
molecular weight heparin ... Cancer #Algorithm #Anticoagulation ... #Management #Hematology ... #Oncology
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 The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
thrombin #clot #PT #PTT ... diagnosis #models #hematology ... pathophysiology #anticoagulation ... Rivaroxaban #Edoxaban #heparin
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
• Secondary Causes ... deficiencies - PNH ... Cholesterol emboli • Septic ... Differential #Diagnosis #hematology ... #rheumatology #
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
cardiac valves (septic ... Hyperhomocysteinemia - Heparin-induced ... coagulation and other causes ... - COVID-19 - PNH ... pathophysiology #hematology
Treatment algorithm for VTE in Malignancy (A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
low-molecular-weight heparin ... Cancer #Algorithm #Anticoagulation ... #Management #Hematology ... #Oncology
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