12 results
diagnosis differential management coagulation abnormal algorithm prolonged ptt cancer doac malignancy pathophysiology treatment vte anticoagulant apixaban arterial bleeding bruising cascade
How to Evaluate an Abnormal APTT Step 1: Is the PT or APTT Artifactually Prolonged? Step 2: Is
Step 1: Is the PT ... K Antagonists, Heparin ... Prolonging the PT ... to identify the cause ... prolonged #diagnosis #hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
for a Prolonged PT ... PT and the aPTT ... (e.g. heparin contamination ... thrombin inhibitors, heparin ... #differential #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
PT and/or aPTT ... unfractionated heparin ... e.g. heparin ... thrombin inhibitors, heparin ... #differential #hematology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
hemoglobin/hemosiderin, Hepatic ... /aPTT MAHA likely ... hemosiderin • PT ... /aPTT normal • ... Management #Algorithm #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
dysfunction (25%) • Hepatic ... deficiency) • HIT: Heparin-PF4 ... 100mg/dL) - Heparin ... INR < 2.3 - APTT ... treatment #management #hematology
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT) Prothrombin Time (PT) - Often Elevated in: • Vitamin
Prothrombin Time (PT ... Prothrombin Time (PT ... elevated in: • Heparin ... thematttsai #PT ... Thromboplastin #laboratory #hematology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
thrombin #clot #PT ... #PTT #diagnosis ... #models #hematology ... pathophysiology #anticoagulation ... Rivaroxaban #Edoxaban #heparin
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis. Currently, edoxaban and rivaroxaban are the only
molecular weight heparin ... Cancer #Algorithm #Anticoagulation ... #Management #Hematology ... #Oncology
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 Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
== NORMAL PT ... level NORMAL PT ... Acquired: • Heparin ... discern these causes ... Differential #Diagnosis #Hematology
Treatment algorithm for VTE in Malignancy (A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
low-molecular-weight heparin ... Cancer #Algorithm #Anticoagulation ... #Management #Hematology ... #Oncology
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