8 results
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
Step 1: Is the PT ... K Antagonists, Heparin ... Direct Thrombin Inhibitor ... to identify the cause ... prolonged #diagnosis #hematology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
for a Prolonged PT ... PT and the aPTT ... (e.g. heparin contamination ... , heparin), Supratherapeutic ... #differential #hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... PT and/or aPTT ... e.g. heparin ... , heparin ... #differential #hematology
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
Prothrombin Time (PT ... Prothrombin Time (PT ... elevated in: • Heparin ... thematttsai #PT ... Thromboplastin #laboratory #hematology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
thrombin #clot #PT ... #PTT #diagnosis ... #models #hematology ... pathophysiology #anticoagulation ... Rivaroxaban #Edoxaban #heparin
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT ... Fibrinogen: ↓ • PT ... Treat primary cause ... Coagulation #diagnosis #causes ... treatment #management #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
== NORMAL PT ... level NORMAL PT ... Acquired: • Heparin ... discern these causes ... Differential #Diagnosis #Hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
tests to detect an inhibitor ... be performed PT ... , PTT, and fibrinogen ... decrease in most cases ... Diagnosis #Workup #Hematology