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diagnosis differential algorithm diffuse lymphadenopathy acronym arterial ascites bandemia bleeding bruising cbc childhood coagulation dic disseminated embolism emergencies focal hemeonc
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
Causes of Diffuse ... • Neoplastic (Leukemia ... Lymphadenopathy #LAD ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Lymphoblastic Leukemia ... Lymphadenopathy #LAD ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... activity • ↓ LAP ... -> AML: Blast crises ... count ↑ PLT • ↑ PBS ... #Hematology #Oncology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
promyelocytic leukemia ... Thrombocytopenia • Prolonged ... protein C and S Pathophysiology ... Treat primary cause ... treatment #management #hematology
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
muscle spasms lead ... invade URT & via hematologic ... , altered LOC; septic ... CNS and hematologic ... peds #pediatrics #pathophysiology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Hyperhomocysteinemia - Heparin-induced ... coagulation and other causes ... - COVID-19 - PNH ... Venous #Arterial #pathophysiology ... #hematology #differential
PLATELETS Mnemonic for Causes of Thrombocytopenia P - Platelet Disorders (DIC, ITP, TTP) L - Leukemia, Lymphoma A -
PLATELETS Mnemonic for Causes ... ITP, TTP) L - Leukemia ... Liver Disease, Lab ... Toxin (Drug or Heparin-induced ... Differential #Diagnosis #Hematology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Tissue damage • Leukemia ... hypotension or septic ... shock, 33% had ... neutrophil #WBC #CBC #hematology ... #pathophysiology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
gingivitis or gingival leukemic ... Acquired: • Heparin ... the PT remains prolonged ... discern these causes ... Differential #Diagnosis #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... compounds, alcohol, lead ... Syndromes #diagnosis #hematology ... #oncology
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