14 results
diagnosis differential hemolytic algorithm classification extravascular hemolysis mds myelodysplastic syndrome treatment agglutinin aplastic disease disorders dyspnea hodgkins leukemia lymphoma monoclonal
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... hemoglobinuria (PNH ... (e.g. primary cold ... #diagnosis #hematology ... #anemia
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Warm AIHA • Cold ... • PCH • PNH ... immune-complex hemolytic anemia ... #Hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
for Hemolytic Anemia ... • AIHA: warm, cold ... Other agents ex. lead ... IVIG infusion Intravascular ... classification #hematology
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
Heart failure - CAD ... - Asthma - COPD ... - Water - Pus ... Transverse myelitis • Hematology ... : - Anemia •
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
• Symptoms of anemia ... • hemolytic anemia ... the RBCs causing intravascular ... disease #hemolytic #anemia ... #hematology #diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... practices that could ... HCV testing - Lab ... changes), high MCV anemia ... #Workup #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
diagnosis: 70 years old ... , ~10,000 new cases ... cytopenias (usually anemia ... #treatment #hematology ... #oncology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... platelet decrease - PNH ... Agglutination - Cold ... Diagnosis #Algorithm #workup ... #hematology #testing
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... and petechiae Causes ... Anticonvulsants - Gold ... #oncology #hematology ... #diagnosis #management
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Amyloidosis (CVS+PNS ... (-) hemolytic anemia ... due to cold IgG ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
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