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diagnosis differential algorithm lad leukemia chronic cll diffuse hodgkins localized lymphocytic management monoclonal blood cell classification comparison disorders extravascular gammopathies
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
Causes of Diffuse ... and Localized Lymphadenopathy ... Neoplastic (Leukemia, Lymphoma ... ) #Diffuse #Focal ... #Hematology #Oncology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
Causes of Localized ... Lymphadenopathy ... #Localized #Focal ... #Lymphadenopathy ... #Hematology #Oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Lymphadenopathy ... Non-Hodgkin's Lymphoma ... • Hodgkin's Lymphoma ... #Hematology #Oncology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
, Auer rod • Lymphoid ... Lymphadenopathy ... Pelger-Huet, Macrocytic anemia ... Proliferation • Lymphoid ... Blood #Disorders #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
- Pruritus: (focal ... disease: B symptoms, lymphadenopathy ... • Other hematologic ... NonHodgkins #comparison #oncology ... #differential #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... - infiltrates (anemia ... and secondary lymphoid ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
early symptoms • Lymphadenopathy ... Exam/Signs: • Lymphadenopathy ... • Neutropenia, anemia ... Leukemia #diagnosis #workup ... #oncology #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Presentation: • Lymphadenopathy ... Weight loss • Anemia ... Workup: • Full ... classification #hematology ... #oncology #management
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... hemoglobinuria (PNH ... e.g. lupus, CLL, lymphoma ... differential #diagnosis #hematology ... #anemia
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
5) Symptoms of anemia ... to large cell lymphoma ... marrow failure with anemia ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
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