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diagnosis differential management algorithm mds anemia aplastic arterial ascites cancer chronic classification dermatology embolism emergencies gammopathies gap globulin hemeonc hodgkins
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
is of B-cell lineage ... -> AML: Blast crises ... count ↑ PLT • ↑ PBS ... • Tumor lysis syndrome ... #Hematology #Oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... Syndrome (MD) - ... transformation to acute leukemia ... Management #treatment #hematology ... #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Chronic Myelogenous Leukemia ... Cell Leukemia ... Workup: • Complete ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
is identical to ... • Richter’s Syndrome ... syndrome • Smoldering ... #diagnosis #workup ... #oncology #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
vera (PV) • Myelodysplastic ... syndrome • Myelofibrosis ... Chronic myeloid leukemia ... (CML) - Dr. ... #hematology #secondary
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
Causes of false- ... amyloidosis Other causes ... plasmacytoma, POEMs syndrome ... MGUS #diagnosis #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... • Hypocellular myelodysplastic ... virus (EBV) • Leukemia ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
general feeling of ill ... Causes: - Idiopathic ... , breast CA - Hematologic ... - Lupus - Leukemia ... #oncology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
• Nephrotic Syndrome ... Ischemic Liver, IBD ... considered in all ... coagulation and other causes ... pathophysiology #hematology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Better call hematology ... JAK2 V617F) and MPNs ... about secondary causes ... you’ll do a good workup ... #hematology
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