11 results
4-T Score for the Likelihood of Heparin Induced Thrombocytopenia
 - Thrombocytopenia - Compare the highest platelet
count
4-T Score for the ... - Thrombocytopenia ... Other potential cause ... ~68%) #4TScore ... Likelihood #Diagnosis #Hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
♀, ↑Age, ESRD Pathophysiology ... → Calculate 4T score ... • If 4T score ... Diagnosis #Management #Treatment ... #Hematology #HemeOnc
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... deficiency) • HIT ... Treat primary cause ... #treatment #management ... #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
inflammation • Thrombocytopenia ... : - Thrombocytopenia ... necrosis) • VIT ... deficiencies - PNH ... Differential #Diagnosis #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Hematological: - HIT ... Heparin-induced thrombocytopenia ... coagulation and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
: 2 hit mechanism ... without other cause ... : 33% • Treatment ... with pulmonary edema ... Transfusion #Reactions #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP Score ... -> AML: Blast crises ... Pruritis after hot ... infiltrates (anemia, thrombocytopenia ... #Leukemia #Hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... membrane into the CNS ... collection with EDTA Pathophysiology ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
infections/fevers • Thrombocytopenia ... and petechiae Causes ... - HCV - HIV ... aplastic anemia Treatment ... Anemia #oncology #hematology
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
wasting, anemia, edema ... deficiencies • Vit ... cutaneous vasculitis, thrombocytopenia ... , or any other cause ... vasculitis Treatment