10 results
Considerations for Crystalloids - 0.9% NS vs LR vs Plasma-Lyte
 - Causes hyperkalemia?
 - Safe to
hyperkalemia? ... patients with hyperkalemia ... - Causes lactic ... #Crystalloids #pharmacology ... #indications #comparison
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Side Effects: Edema ... constipation, diarrhea, nausea ... ); nausea, vomiting ... #medications #pharmacology ... #table #comparison
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison

Composition of LR:
 • Sodium 130 mEq/L
 •
) - Comparison ... Is Dangerous in Hyperkalemia ... shift • Saline Causes ... • Saline May Cause ... #comparison #pharmacology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
and Management ... S/Sx: Most pts ... Weakness, cramping, nausea ... only if no clear cause ... caution in HTN & edema
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
effusions). 1/5 pts ... endomyocardial biopsy Pharmacology ... Jcortesizaguirr #HFrEF #heartfailure ... #diagnosis #management ... #cardiology #pharmacology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
irrigation • Management ... Acute pulmonary edema ... Hyponatremia • Hypercalcemia ... Kidney stones caused ... Diuresis #Nephrology #Pharmacology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
JVD, Orthopnea/PND ... the determined cause ... differential #algorithm #management ... table #foamed #heartfailure ... icu #clinical #pharmacology
Overview of antifungal agents benefits, weaknesses, and adverse effects in the treatment of Coccidioidomycosis.
Fluconazole - Low
and peripheral edema ... hypertension, peripheral edema ... #valleyfever #management ... #antifungals #comparison ... #table #pharmacology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... Xerostomia • Dental caries ... Nephrogenic DI Hematologic ... lubricants • Pharmacologic ... #Diagnosis #Management
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
generalized subcutaneous edema ... Pts have more ... Muscle atrophy may cause ... Dermatomyositis #diagnosis #management ... dermatology