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rheumatology treatment dermatology cardiology differential erythematosus sle syndrome systemic algorithm anemia antinxp2 antinxp2dm atlas basics cardiomyopathy cerebritis chf clinical cns
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Causes Intravascular ... hemoglobinuria (PNH ... usually IgG) (e.g. lupus ... #diagnosis #hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... Summary • Epidemiology ... Positive in 60-80% of cases ... #Management #Summary ... #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
autoantibodies that will cause ... permeability Diagnosis ... #neurology #rheumatology ... #cerebritis #diagnosis ... #management #treatment
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Kawasaki Disease (KD) - Diagnosis and Management Summary Kawasaki Disease (KD) is the most common vasculitis of
Summary Kawasaki ... Mucositis, Rash, Hand edema ... , Cough • +/-Nausea ... palms or soles, edema ... KD #vasculitis #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... lymphoma (DLBCL, intravascular ... Drugs, Unknown cause ... #management #treatment ... #summary #rheumatology
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
Cardiomyopathy - Summary ... exclude other causes ... Differential Diagnosis ... , LE edema • Minority ... Cardiomyopathy #diagnosis
Pheochromocytoma - Diagnosis and Management Summary 10 percent rule = 10% of pheochromocytomas are extra-adrenal, multiple, bilateral,
Pheochromocytoma - Diagnosis ... Summary 10 percent ... malignant, pediatric cases ... and Signs: 50% pts ... with pulmonary edema
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO Syndrome Summary ... blisters containing pus ... Rule out other causes ... #diagnosis #management ... #Dermatology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
JVD, Orthopnea/PND ... and Peripheral Edema ... the determined cause ... #algorithm #management ... icu #clinical #pharmacology
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