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diagnosis rheumatology erythematosus syndrome treatment activation algorithm antinxp2 antinxp2dm cardiology cardiomyopathy cerebritis clues cns comparison dermatomyositis differential dress druginduced macrophage
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
of Systemic Lupus ... autoantibodies that will cause ... #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Manifestations: Malar rash ... Positive in 60-80% of cases ... #lupus #Systemic ... #Summary #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... months to years) Systemic ... Manifestations: Malar rash ... #table #rheumatology ... #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Malignancy (e.g. hematologic ... lower extremity edema ... • May involve PNS ... #Systemic #Lupus
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
everywhere) 2) A rash ... rosacea) 3) Limb oedema ... 6) An annular rash ... #diagnosis #sle ... #clues #system
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Classified among the secondary ... Petechial or purpuric rash ... [SLE], AOSD) • ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Eosinophilia and Systemic ... extensive skin rash ... • Facial Edema ... in 70% of cases ... DRESS #Syndrome #dermatology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
frequently affected systems ... Better call hematology ... some time, let’s see ... JAK2 V617F) and MPNs ... Algorithm #workup #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
other diseases • Secondary ... overlaps with RA, SLE ... Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... #Diagnosis #Management
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... LV thrombus, RV systolic ... , LE edema • Minority ... of Pts: cardiogenic ... Delivery • Stable
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