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diagnosis management antimda5 antimda5dm antinxp2 antinxp2dm coagulation comparison dic disseminated hemophagocytic hlh intravascular lymphohistiocytosis reactions sapho syndrome taco trali transfusion
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
ANTI-MDA5 DERMATOMYOSITIS ... blue-purple) rash with edema ... Men • ~50% of cases ... #rheumatology # ... dermatology #diagnosis
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
without other cause ... : 33% • Treatment ... with pulmonary edema ... Transfusion #Reactions #hematology ... diagnosis #comparison #table
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
+ Bleeding Treatment ... Treat primary cause ... Coagulation #diagnosis #causes ... #treatment #management ... #hematology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
Pts have more ... Muscle atrophy may cause ... positive patients Treatment ... diagnosis #management #rheumatology ... #dermatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... Rule out other causes ... and lower jaw Treatment ... SAPHO #Syndrome #Rheumatology ... diagnosis #management #Dermatology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
Lymphohistiocytosis (HLH) Treatment ... (depending on CNS ... autoimmune disease, treatment ... Options for severe cases ... #management #hematology
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