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diagnosis differential treatment acr2021 algorithm antibodies classification dermatology diseases granulomatosis guidelines lupus sle ana antibody antineutrophil antinuclear antinxp2 antinxp2dm associations
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Anti-dsDNA (in 70% of cases ... seen in 30—70% of cases ... Vasculitis: • ... Renal-limited vasculitis ... antibodies #diagnosis #rheumatology
Eosinophilic Granulomatosis with Polyangiitis (EGPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021 Guidelines • Active
(EGPA) - ANCA Vasculitis ... Management Algorithm ... alone in select pts ... #ANCA #Vasculitis ... Guidelines #algorithm #rheumatology
Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021
(MPA) - ANCA Vasculitis ... Management Algorithm ... #MPA #ANCA #Vasculitis ... #Management #Treatment ... Guidelines #algorithm #rheumatology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
- Vasculitis, e.g ... - Vasculitis, e.g ... Microscopic polyangiitis ... diseases #diagnosis #table ... #rheumatology #
Diagnosis and management of Polyarteritis Nodosa (PAN) Chapel Hill 2012 definition: Necrotizing vasculitis ofmedium or small arteries
Diagnosis and management ... associated with ANCA ... Cardiomyopathy - CNS ... PolyarteritisNodosa #Rheumatology ... #Diagnosis #Management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- ANCA specific ... • Microscopic Polyangiitis ... tract, and often causes ... Vasculitis: + MPO-ANCA ... differential #diagnosis #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
• Secondary Causes ... deficiencies - PNH ... Cryoglobulinemia (MIXED) • ANCA ... Differential #Diagnosis #hematology ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
: Microscopic polyangiitis ... Granulomatosis with Polyangiitis ... Granulomatosis with Polyangiitis ... tract, and often causes ... Differential #Diagnosis #Rheumatology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Summary Autoimmune ANCA ... vasculitis (AAV ... Auto-antibodies: ANCA ... Goodpasture's cause ... differential #diagnosis #management
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... DDX: • ANCA (Antineutrophil ... EGPA, microscopic polyangiitis ... classification #rheumatology
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