9 results
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
replicates within CNS ... invade URT & via hematologic ... CNS and hematologic ... persists as skin lesions ... peds #pediatrics #pathophysiology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... autoantibodies that will cause ... Puncture, EEG Treatment ... #neurology #rheumatology ... diagnosis #management #treatment
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
atherosclerotic lesions ... coagulation and other causes ... - COVID-19 - PNH ... Venous #Arterial #pathophysiology ... #hematology #differential
Rickettsialpox Eschar

40 homeless male from NY admitted with fever, chills, headache, myalgias. Diagnosis?
Rickettsialpox R akari classic
Rickettsialpox Eschar ... Can have 20-40 lesions ... Pts can recover ... clinical #photo #skinrash ... #dermatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... + Bleeding Treatment ... Treat primary cause ... #treatment #management ... #hematology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... that results in CNS ... compressive cord lesion ... • Infectious causes ... Transverse Myelitis Treatment
Cutaneous Mucormycosis Eschar
30 M HIV cd4 10 VL 30k traumatic injury of arm few months ago
immunosuppressed pts ... cutaneous mucor cases ... from center of lesion ... therapy), some cases ... #dermatology #skin
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... Pustular skin lesions ... Rule out other causes ... and lower jaw Treatment ... SAPHO #Syndrome #Rheumatology
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
subcutaneous edema Pts ... Auricular skin lesions ... Muscle atrophy may cause ... positive patients Treatment ... #dermatology