11 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
hemorrhagic skin lesions ... deficiencies - PNH ... • HCV, HBV Not ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Hematological: - HIT ... atherosclerotic lesions ... coagulation and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... deficiency) • HIT ... Treat primary cause ... #treatment #management ... #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
: 2 hit mechanism ... without other cause ... : 33% • Treatment ... : No • Treatment ... Transfusion #Reactions #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... : - Genetic lesions ... - HIV • Immune ... aplastic anemia Treatment ... Anemia #oncology #hematology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... Pustular skin lesions ... Rule out other causes ... and lower jaw Treatment ... diagnosis #management #Dermatology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... that results in CNS ... • Infectious causes ... simplex virus, HIV ... Transverse Myelitis Treatment
Rickettsialpox Eschar

40 homeless male from NY admitted with fever, chills, headache, myalgias. Diagnosis?
Rickettsialpox R akari classic
Can have 20-40 lesions ... Pts can recover ... chickenpox, vzv, hsv ... clinical #photo #skinrash ... #dermatology
Cutaneous Mucormycosis Eschar
30 M HIV cd4 10 VL 30k traumatic injury of arm few months ago
Mucormycosis Eschar 30 M HIV ... immunosuppressed pts ... malnutrition, HIV ... from center of lesion ... Mucormycosis #Eschar #dermatology
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
subcutaneous edema Pts ... Auricular skin lesions ... Muscle atrophy may cause ... positive patients Treatment ... #dermatology