9 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... autoantibodies that will cause ... thrombosis and/or blood-brain ... Erythematosus #SLE #CNS ... cerebritis #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Thromboembolism (7%) • CNS ... + Bleeding Treatment ... Treat primary cause ... #treatment #management ... #hematology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... ruled out • Brain ... brain and/or optic ... Transverse Myelitis Treatment ... Myelitis #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    • Dexamethasone
Lymphohistiocytosis (HLH) Treatment ... (depending on CNS ... autoimmune disease, treatment ... Options for severe cases ... #management #hematology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... - MRI: inflammation ... and lower jaw Treatment ... #diagnosis #management ... #Dermatology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... Serum Copper • Chest ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Most cases are related ... MI, stroke, DVT/ ... Thrombocythemia #ET #hematology ... #diagnosis #management ... #hematology
Cryptococcal meningitis on T2 MRI
30 M from sub-Saharan Africa presents w/ progressive Headache x1 mo, +neck
low glucose) CNS ... Nausea & vomiting ... Standard treatment ... #Brain #clinical ... #radiology
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
subcutaneous edema Pts ... Muscle atrophy may cause ... positive patients Treatment ... Dermatomyositis #diagnosis #management ... dermatology