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diagnosis differential classification cryoglobulinemia hydroxychloroquine sle adverseeffects benefits cerebritis cns cryoglobulinemic cryoglobulins dermatology erythematosus levels measurement mixed monoclonal neurology nonhcv
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
half-life = 40 days ([HCQI ... Hydroxychloroquine #HCQ ... Measurement #SLE #rheumatology ... #pharmacology # ... levels #lupus #management
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
• Secondary Causes ... deficiencies - PNH ... • HCV, HBV Not ... Differential #Diagnosis #hematology ... #rheumatology #
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group < 5%
Non-HCV infectious ... - Diagnosis, causes ... and management ... #Rheumatology # ... Cryoglobulinemic #Diagnosis #Management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... autoantibodies that will cause ... Erythematosus #SLE #CNS ... #neurology #rheumatology ... cerebritis #diagnosis #management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... inflammation Others: • Lupus ... such as systemic lupus ... • HIV • HBV HCV ... differential #diagnosis #rheumatology
Hydroxychloroquine - Risks and Benefits in Lupus Benefits: ↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
and Benefits in Lupus ... Hydroxychloroquine #hcq ... Risks #Benefits #Lupus ... #pharmacology # ... #sideeffects #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... • Infections: HCV ... (e.g. systemic lupus ... classification #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Zone Lymphoma (HCV ... Amyloidosis (CVS+PNS ... Autoimmunity: • -MM/WM: Vasculitis ... to cold IgG • Lupus ... Paraproteinemias #Hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... lubricants • Pharmacologic ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
including systemic lupus ... ANCA-associated vasculitis ... histopathologic changes in LNs ... TAFRO #diagnosis #management ... #rheumatology #
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