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diagnosis differential cns management neurology algorithm antiphospholipid apls arthritis cerebritis cryofibrinogenemia embolism erythematosus gout gouty hypercoagulable leigh lesions lupus msk
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Kasabach-Merritt syndrome ... deficiencies - PNH ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
• Nephrotic Syndrome ... considered in all cases ... coagulation and other causes ... - COVID-19 - PNH ... pathophysiology #hematology
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
Diagnosis- Compatible syndrome ... + MRI lesions + ... RingEnhancing #Lesions #Brain ... differential #diagnosis #causes ... #radiology #neurology
Leigh Syndrome History: 19-month-old girl with hypotonia, developmental delay, failure to thrive, and bilateral optic disc
Leigh Syndrome ... patterns (this case ... #Clinical #MRI ... #Brain #Diagnosis ... #Radiology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... autoantibodies that will cause ... thrombosis and/or blood-brain ... #neurology #rheumatology
Gout (Gouty Arthritis) - MSK Radiology Imaging Findings: • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Arthritis) - MSK Radiology ... Case description ... • PVNS/Giant Cell ... #clinical #Radiology ... diagnosis #msk #rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... Rule out other causes ... - MRI: inflammation ... #Rheumatology # ... diagnosis #management #Dermatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cryoglobulins • Negative causes ... to medium-sized arteries ... Antiphospholipid syndrome ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
• Coronary arteries ... oligoclonal bands • MRI ... tract, and often causes ... Thrombosis and arterial ... Differential #Diagnosis #Rheumatology
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Antiphospholipid Syndrome ... - 1 or more clinical ... episodes of arterial ... maternal chromosomal causes ... Algorithm #diagnosis #hematology
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