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diagnosis differential management clinical oncology syndrome blood product reactions antimda5 antimda5dm antinxp2 antinxp2dm arterial atlas autoimmune basics cardiology coagulation compared
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
Cutaneous manifestations ... ulcerations • Skin ... • Skin vasculopathies ... #rheumatology # ... dermatology #diagnosis
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... deficiencies - PNH ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
If you haven't seen it, flecainide can cause significant yellowing of the skin and eyes.
flecainide can cause ... yellowing of the skin ... sideeffects #clinical #photo ... #nails #cardiology ... #dermatology #discoloration
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Most common extra cutaneous ... Causes: - Idiopathic ... , breast CA - Hematologic ... multiforme - Dermatomyositis ... Syndrome #diagnosis #dermatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... gangrenosum • Cutaneous ... thrombosis+Pulm HTN+skin ... Amyloidosis (CVS+PNS ... Paraproteinemias #Hematology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
subcutaneous edema Pts ... in the neck Cutaneous ... Muscle atrophy may cause ... diagnosis #management #rheumatology ... #dermatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Testosterone - Coumadin skin ... considered in all cases ... coagulation and other causes ... - COVID-19 - PNH ... pathophysiology #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Still disease, dermatomyositis ... Non-autoimmune rheumatologic ... • May involve PNS ... Erythematosus #Diagnosis #Rheumatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Thromboembolism (7%) • CNS ... involvement (2%) Cutaneous ... Treat primary cause ... Coagulation #diagnosis #causes ... treatment #management #hematology
Primary Dermatological Lesions Primary lesions are physical changes in the skin considered to be caused directly by
considered to be caused ... scabitic mite or by cutaneous ... lesions that contain pus ... dilatation of small cutaneous ... #Diagnosis #Dermatology
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