13 results
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Aplastic Anemia ... Treatment: • Consider ... • Associated PNH ... #management #treatment ... #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Headaches • Pale skin ... anemia Treatment ... #hematology #diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... old, ~10,000 new cases ... cytopenias (usually anemia ... only curative treatment ... #hematology #oncology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... - Hemolytic anemia ... deficiencies - PNH ... Differential #Diagnosis #hematology ... #rheumatology #
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... Out Secondary Causes ... • AnemiaAplastic ... factor (GCSF) treatments ... Syndromes #diagnosis #hematology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
bone, joint, and skin ... blisters containing pus ... Rule out other causes ... and lower jaw Treatment ... SAPHO #Syndrome #Rheumatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... • Neutropenia, anemia ... Pure red cell aplasia ... microglobulin Treatment ... workup #oncology #hematology
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
Causes of Neutropenia ... hypertension and/or drug treatment ... Megaloblastic anemia-rare ... white blood cell aplasia ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... count ↑ PLT • ↑ PBS ... - infiltrates (anemia ... CLL -> Invade Skin ... #Leukemia #Hematology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Lacrimal swelling • Skin ... Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology