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diagnosis management algorithm differential workup leukemia syndrome chronic dermatology lymphocytic mds myelodysplastic radiology sicklecell treatment anthracycline antinxp2 antinxp2dm arterial arteritis
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... count ↑ PLT • ↑ PBS ... Transformation: • Complication ... #Leukemia #Hematology ... #Oncology #Diagnosis
Algorithm for the Evaluation and Management of Sickle Cell Crises Clinical Manifestations and Management #Diagnosis #Management #Hematology #SickleCell
Management of Sickle Cell ... Crises Clinical ... Diagnosis #Management #Hematology ... #SickleCell #Complications
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... • Risks: infection ... Allogeneic stem cell ... Management #treatment #hematology ... #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... kinase (BTK) Complications ... leukemia • GI complications ... diagnosis #workup #oncology ... #hematology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
focal lesions on MRI ... Causes of false- ... amyloidosis Other causes ... MGUS #diagnosis #hematology ... #oncology
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... Pain in Sickle Cell ... other orthopedic complications ... • XR, MRI to ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
immunophenotype Clinical ... thrombocytopenia Complications ... chemotherapy for low-risk ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Gout (Gouty Arthritis) - MSK Radiology Imaging Findings: • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Case description ... prior signs or clinical ... • PVNS/Giant Cell ... #clinical #Radiology ... diagnosis #msk #rheumatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
• Acquired Risk ... considered in all ... cardiovascular risk ... coagulation and other causes ... pathophysiology #hematology
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care TRICC - NEJM 1999 -
Major Clinical Trials ... unnecessary and cause ... in critically ill ... the deadliest complication ... Transfusion #Thresholds #Hematology
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