11 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... • Risks: infection ... transformation to acute ... only curative treatment ... #hematology #oncology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Attempt if high risk ... organ dysfuxtion, ICU ... diagnosis #management #hematology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... -> AML: Blast crises ... Transformation: • Complication ... #Leukemia #Hematology ... #Oncology #Diagnosis
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... Avoid ARBs • ICD ... Thromboembolic complications ... diagnosis #management #cardiology ... #treatment
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
important to recognize Acute ... the determined cause ... algorithm #management #cardiology ... #criticalcare #icu ... #clinical #pharmacology
The crusade against “Ab”Normal Saline continues.  This is a non-physiologic fluid that can harm our
K+ in the ECF causes ... Hyperkalemia, a complication ... with an increased risk ... management #diagnosis #treatment ... #pharmacology #
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... effusion, INC risk ... Malignancy Risk ... Adenocarcinoma Treatment ... lubricants • Pharmacologic
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
carries a variable risk ... Significance (ICUS ... and reducing the risk ... Syndromes #diagnosis #hematology ... #oncology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... syndrome): - Hematologic ... mg/dL or > 25 % rise ... Treat underlying cause ... interventional radiology
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity
Anthracyclines cause cardiomyopathy:
 ✖ Reduction in left ventricular ejection fraction
Anthracyclines cause ... LVEF) can occur acutely ... ) and initiate treatment ... Cardiotoxicity #cardiology ... #oncology #pharmacology