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management differential mds myelodysplastic pathophysiology treatment algorithm alkaline arterial autoimmune brain cardiomyopathy chronic classification clinical cll coronavirus covid19 crypto cryptococcal
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... count ↑ PLT • ↑ PBS ... Transformation: • Complication ... #Hematology #Oncology ... #Diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... • Risks: infection ... transformation to acute leukemia ... Management #treatment #hematology ... #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... thrombocytopenia Complications ... chemotherapy for low-risk ... #oncology #hematology ... #hemeonc #diagnosis
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Most cases diagnosed ... prematurely • risk ... membrane into the CNS ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
- Differential Diagnosis ... • Acquired Risk ... considered in all ... coagulation and other causes ... pathophysiology #hematology
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology Pulse pressure is the difference between the systolic blood
• Sepsis Complications ... with an increased risk ... • Mitchell et al ... • Increased risk ... #cardiology
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
accounts for 21% of all ... immunocompetent population Risk ... symptoms, unexplained hematologic ... to 50% of PTLD cases ... Lymphoproliferative #Disorders #oncology
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... Differential Diagnosis ... Thromboembolic complications ... Cardiomyopathy #diagnosis ... #management #cardiology
UCSF COVID-19 Adult Clinical Evaluation Guide - Updated April 10 2020 Clinical Presentation • Fever: hospitalized pts but
: hospitalized pts ... in <35% • AST/ALT ... 7-28% -> Incr risk ... complications, ... Evaluation #Guide #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
carries a variable risk ... • Hairy Cell Leukemia ... and reducing the risk ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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