8 results
diagnosis management myelodysplastic anemia anthracycline cardiomyopathy cardiotoxicity chemotherapy emergencies essential et hemeonc her2 leukemia myelodysplasia oncologic peripartum pharmacology syndrome syndromes
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... old, ~10,000 new cases ... transformation to acute ... Myelodysplastic #Syndrome #MDS ... #hematology #oncology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... neutropenic fever) Complications ... Can progress to MDS ... or acute leukemia ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
ALL (Acute Lymphoblastic ... -> AML: Blast crises ... Transformation: • Complication ... #Leukemia #Hematology ... #Oncology #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
carries a variable risk ... • Anemia • Aplastic ... and reducing the risk ... Syndromes #diagnosis #hematology ... #oncology
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... • Minority of Pts ... Thromboembolic complications ... diagnosis #management #cardiology ... #treatment
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Most cases are related ... , symptoms and complications ... generally requires all ... PV, MDS, CML) Treatment ... transformation into MDS
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
syndrome): - Hematologic ... mg/dL or > 25 % rise ... Treat underlying cause ... interventional radiology ... AML (~20 %) and APL
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity Anthracyclines cause cardiomyopathy: ✖ Reduction in left ventricular ejection fraction
Anthracyclines cause ... LVEF) can occur acutely ... ) and initiate treatment ... Cardiotoxicity #cardiology ... #oncology #pharmacology
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