11 results
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... ) Pathophysiology ... = nonspecific (nausea ... Monitor and Treat Complications ... Pregnancy #hepatology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver ... prematurely • risk ... membrane into the CNS ... collection with EDTA Pathophysiology ... Phosphatase: • Other causes
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
• Acquired Risk ... Syndrome, Ischemic Liver ... cardiovascular risk ... Venous #Arterial #pathophysiology ... #hematology #differential
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... DIC • Severe Liver ... Treat primary cause ... #treatment #management ... #hematology
Nutrition in Cirrhosis: Dos and Don’ts
Screening:
 • Patients at risk for RFH-Nutritional Prioritizing Tool
 • Low
• Patients at risk ... ) • Advanced liver ... you do for other complications ... Cirrhosis #diet #management ... #hepatology #pathophysiology
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
immunocompetent population Risk ... in lung>heart>liver ... symptoms, unexplained hematologic ... Lymphoproliferative #Disorders #oncology ... #diagnosis #management
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... Risk Factors and ... • Minority of Pts ... Thromboembolic complications ... #cardiology #treatment
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
increased infection risk ... noninfectious complications ... disease • Liver ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
effusion, INC risk ... vasculitis: 10%-16% Liver ... Nephrogenic DI Hematologic ... Malignancy Risk ... #Diagnosis #Management
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... syndrome): - Hematologic ... mg/dL or > 25 % rise ... Treat underlying cause ... interventional radiology