7 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... of Systemic Lupus ... autoantibodies that will cause ... thrombosis and/or blood-brain ... Erythematosus #SLE #CNS
Alice in Wonderland Syndrome
What? Metamorphophsia - Distortions of the visual perceptions with changes in size (micro
CNS: parietal ... lobe • Retina • Systemic ... encephalitis) • Brain ... • Psychiatric disorders ... diagnosis #neurology #differential
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
affecting the brain ... (CNS) involvement ... Inflammatory causes ... optica spectrum disorder ... #inflammatory #differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... • May involve PNS ... and CNS • Headache ... Thrombosis highest risk
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
syndrome): - Hematologic ... mg/dL or > 25 % rise ... Treat underlying cause ... ) - Symptoms: CNS ... ) - Symptoms: CNS
Differential Diagnosis: New-Onset Seizure in the Elderly

STRUCTURAL:
 • Stroke/TIA, Subdural hematoma, mass
 • Traumatic Brain Injury
Differential Diagnosis ... • Traumatic Brain ... abscess • Sepsis: Systemic ... tenfold increased risk ... cardiovascular causes
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... aspiration > 50% of pts ... • Conduction system ... statins - probably caused ... #differential #