21 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... diagnosis and risk-stratification ... • Risks: infection ... Management #treatment #hematology ... #oncology
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Indications and Pharmacology ... : Urine Common Uses ... fatigue; Increases risk ... #Indications #Pharmacology ... #hematology
Hydroxychloroquine - Risks and Benefits in Lupus
Benefits:
↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
Hydroxychloroquine - Risks ... Cardiovascular risk ... rare with ~100 cases ... Benefits #Lupus #pharmacology ... #sideeffects #rheumatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
• Acquired Risk ... cardiovascular risk ... coagulation and other causes ... - COVID-19 - PNH ... pathophysiology #hematology
Drugs affecting the cardiac action potential. The sharp rise in voltage ("0") corresponds to the influx
The sharp rise in ... #Pathophys #Pharmacology ... #Cardiology #Antiarrhythmics ... #Classes #Effect
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... -> AML: Blast crises ... count ↑ PLT • ↑ PBS ... #Leukemia #Hematology ... #Oncology #Diagnosis
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
immunocompetent population Risk ... symptoms, unexplained hematologic ... to 50% of PTLD cases ... Lymphoproliferative #Disorders #oncology
Acute Atrial Fibrillation - Initial Options for Rate Control
Diltiazem IV
 •  Rapid onset and rapidly
with ADHF • Risks ... IV bolus can cause ... • Does not cause ... Rate #Control #pharmacology ... #management #cardiology
Clinically Significant Cardiovascular Drug-Drug Interactions With OTC Supplements and Herbal Products
Angiotensin-Converting Enzyme Inhibitors (ACEIs)
 • Night-blooming
Increases bleeding risk ... increased bleed risk ... vera, Licorice - Causes ... supplementals #herbal #pharmacology ... #DDI #table #cardiology
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
an underlying cause ... circulation = risk ... Better call hematology ... JAK2 V617F) and MPNs ... Algorithm #workup #hematology