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diagnosis differential management algorithm eosinophilia rash treatment workup anemia disease dress drugreaction hemeonc monoclonal skin skinrash ucsdh apml chronic cll
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
Causes of Diffuse ... • Neoplastic (Leukemia ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... transformation to acute leukemia ... Management #treatment #hematology ... #oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Neoplastic: - Leukemia ... Lymphoblastic Leukemia ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Hypersegmented neutrophil in a case of acute myeloid leukemia. Dysplastic neutrophils are typically hypolobated but can be
neutrophil in a case ... acute myeloid leukemia ... neutrophils #AML #Clinical ... #Hematology #Pathology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... count ↑ PLT • ↑ PBS ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Hematology #Oncology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Leukemia, Tumour ... Non-lmmune: • HELLP Syndrome ... Diagnosis #Algorithm #Causes ... #Hematology
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia ... features in most cases ... promyelocytic #leukemia ... APML #Pathology #Hematology ... #Clinical #Smear
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... Myelodysplastic syndrome ... Chronic myeloid leukemia ... Differential #Diagnosis #Causes ... #hematology #secondary
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... Acute Eosinophilic Leukemia ... Hypereosinophilic Syndrome ... Chronic Eosinophilic Leukemia ... #hematology
Recurrent / Breakthrough DVT During Anticoagulation Subtherapeutic Anticoagulation Hypercoagulable State - Antithrombin deficiency - Hypercoagulability ot
APLS - MPN/PNH ... Structural - Pelvic masses ... - May-Thurner syndrome ... anticoagulation #hematology
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