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Thrombotic Microangiopathies In Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Microangiopathies In Systemic Lupus ... Erythematosus #SLE #hematology ... #rheumatology # ... differential #diagnosis ... #causes
Differential Algorithm for the Causes of thrombocytopenia 

#Diagnosis #Hematology #Thrombocytopenia #Causes #Differential
Differential Algorithm ... for the Causes ... of thrombocytopenia ... #Diagnosis #Hematology ... #Causes #Differential
Drug-Induced Thrombocytopenia
The diagnosis of drug-induced thrombocytopenia can be made only by demonstrating resolution of thrombocytopenia once
Drug-Induced Thrombocytopenia ... #Diagnosis #Hematology ... #Thrombocytopenia ... #Differential # ... #Medications #Causes
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... - Differential ... effect following treatment ... following EtOH induced thrombocytopenia ... #Hematology
Causes of Thrombocytopenia.
Platelet counts may be depressed because of decreased production or due to increased platelet
Causes of Thrombocytopenia ... #Diagnosis #Hematology ... #Thrombocytopenia ... #Differential # ... Causes #Production
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Often hard to differentiate ... distinction has HUGE treatment ... and first-line treatment ... Microangiopathy #thrombocytopenic ... Diagnosis #Table #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... Platelet Disorders - Differential ... l MD SOAP) - Risks ... or if a primary hematologic ... #Workup #hematology
4-T Score for the Likelihood of Heparin Induced Thrombocytopenia
 - Thrombocytopenia - Compare the highest platelet
count
Other potential cause ... Low probability (risk ... Intermediate probability (risk ... High probability (risk ... Likelihood #Diagnosis #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential ... #Differential # ... Diagnosis #Algorithm #Causes ... #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... : - Thrombocytopenia ... deficiencies - PNH ... #Diagnosis #hematology ... #rheumatology #