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management differential algorithm oncology anemia comparison dermatology lupus table hemeonc hemolysis hemolytic hemophagocytic hlh lymphohistiocytosis neurology pathophysiology sle disease erythematosus
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. TTP/HUS indicates thrombotic
Algorithm for workup ... of thrombocytopenia ... hemolytic uremic syndrome ... , Hematology 2012 ... , p 193 #Diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... and Workup History ... l MD SOAP) - Risks ... #Causes #Workup ... #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential Diagnosis ... ITP • SLE • CLL ... Non-lmmune: • HELLP Syndrome ... #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... infiltrates (anemia, thrombocytopenia ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... • Risks: infection ... Allogeneic stem cell ... #hematology #oncology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... - Differential Diagnosis ... effect following treatment ... following EtOH induced thrombocytopenia ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... microangiopathy: Thrombotic thrombocytopenic ... hemoglobinuria (PNH ... #hematology #anemia
Algorithm for the Evaluation and Management of Sickle Cell Crises Clinical Manifestations and Management #Diagnosis #Management #Hematology #SickleCell
Management of Sickle Cell ... Crises Clinical ... Management #Diagnosis ... #Management #Hematology ... Manifestations #Workup
4-T Score for the Likelihood of Heparin Induced Thrombocytopenia - Thrombocytopenia - Compare the highest platelet count
Other potential cause ... Low probability (risk ... High probability (risk ... #Likelihood #Diagnosis ... #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... : - Thrombocytopenia ... Kasabach-Merritt syndrome ... deficiencies - PNH ... #hematology #rheumatology
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