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diagnosis differential algorithm rheumatology dyspnea extravascular hemolysis infections infectiousdiseases systemic abg abnormal abnormalities acid acidbase acute aids alkaline alp base
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... • PCH • PNH ... immune-complex hemolytic anemia ... Diagnosis #Algorithm #Causes ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... hemoglobinuria (PNH ... #Causes #differential ... #diagnosis #hematology ... #anemia
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
- Water - Pus ... Barre - ALS - Transverse ... myelitis • Hematology ... : - Anemia • ... #pulmonary
Causes of Wide Pulse Pressure - Differential Diagnosis Physiologic: • Advanced age-arteriosclerosis (less compliant arteries) • Well
Causes of Wide Pulse ... conditions) • Severe intravascular ... iron deficiency anemia ... disorders - Chronic ... pulmonary diseases
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... Neoplastic / Hematologic ... • Anemia • ... Obstructive Pulmonary ... Diagnosis #Algorithm #causes
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Iron deficiency anemia ... discoloration) • Chronic ... Muehrcke's Lines - Transverse ... Systemic #Secondary #dermatology ... Diagnosis #Algorithm #causes
Causes of Iron Deficiency - Differential Diagnosis Algorithm • Blood loss: GI (cancer, ulcer, IBD), GU
Causes of Iron Deficiency ... • Iron loss: Intravascular ... hemolysis, (PNH ... athletic training, Pulmonary ... Increased hepcidin: Chronic
Acute and Chronic Causes of Dyspnea - Differential Diagnosis Pulmonary/Chest Wall: • Acute: Trauma, COPD exacerbation, Asthma
Causes of Dyspnea ... Differential Diagnosis Pulmonary ... Pleural effusion, Pulmonary ... : Anemia, Arrhythmia ... hernia, Obesity CNS
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm Relative - Normal RBC Mass / Decreased Plasma Volume
Causes of Polycythemia ... Splenomegaly, Increased PMNs ... Sleep Apnea • Chronic ... Pulmonary Disease ... #Hematology
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
hemolytic anemia ... and/or hypoxia Chronic ... Chronic thromboembolic ... multifactorial mechanisms Hematologic ... #Differential #Causes
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