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diagnosis differential management algorithm myelodysplastic pancytopenia rheumatology syndrome treatment workup abg acid acidbase base bloodgas clinical cutaneous dermatology disorders dyspnea
Aplastic Anemia Summary • Definition • Pathophysiology • DDx: AA vs Hypocellular MDS • Expectation •
Aplastic Anemia ... vs Hypocellular MDS ... @ZhuoerXie #Aplastic ... #Anemia #diagnosis ... #oncology #hematololgy
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... Can progress to MDS ... • Associated PNH ... Medicine @SCVMCMed #Aplastic ... management #treatment #hematology
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
- Water - Pus ... Barre - ALS - Transverse ... myelitis • Hematology ... : - Anemia • ... #pulmonary
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... and petechiae Causes ... #Anemia #oncology ... #hematology #diagnosis
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Non-hemolytic: ACD, Aplastic ... PK, HbC, HbSS, PNH ... Reticulocytosis, MDS ... Matthew Ho, MD ... Differential #Diagnosis #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... cytopenias (usually anemia ... Myelodysplastic #Syndrome #MDS ... Management #treatment #hematology ... #oncology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
PNH 2. ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... MDS • Congenital ... Diagnosis #Algorithm #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
PNH 2. ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... MDS • Congenital ... Diagnosis #Algorithm #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes (MDS ... skin that are caused ... • Anemia • Aplastic ... Syndromes #diagnosis #hematology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... count ↑ PLT • ↑ PBS ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
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