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differential management algorithm myelodysplastic polycythemia rheumatology syndrome abg acid acidbase aplastic base bloodgas disorders dyspnea erythematosus gas interpretation leukemia lupus
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
- Water - Pus ... Barre - ALS - Transverse ... myelitis • Hematology ... : - Anemia • ... #causes #pulmonary
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm Relative - Normal RBC Mass / Decreased Plasma Volume
Causes of Polycythemia ... (Erythrocytosis ... - Differential Diagnosis ... Splenomegaly, Increased PMNs ... #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... cytopenias (usually anemia ... Myelodysplastic #Syndrome #MDS ... #treatment #hematology ... #oncology
Erythrocytosis - Polycythemia Differential Diagnosis Algorithm Elevated Hemoglobin: • Males: Hb > 16.5 g/dL/HCT ≥ 49% •
Erythrocytosis - ... Polycythemia - Acquired Causes ... Hypoxia-driven: Cardiac/pulmonary ... Matthew Ho, MD ... #Algorithm #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... myelodysplastic syndrome (MDS ... Hypocellular/Hypoplastic MDS ... #oncology #hematology ... #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes (MDS ... skin that are caused ... Out Secondary Causes ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... count ↑ PLT • ↑ PBS ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Acid Base Disorders - Blood Gas Interpretation Steps for Blood Gas Interpretation: 1. Acidemia or Alkalemia? 2.
- Differential Diagnosis ... Renal failure (uremia ... Classically” noted with pulmonary ... acidosis: - CNS ... Daniyal Hashmi, MD
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... peripheral neuropathy, transverse ... Disease: • 10%-15% Pulmonary ... , INC risk PE, Pulmonary ... Nephrogenic DI Hematologic
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... • May involve PNS ... neuropathy • Transverse ... lymphopenia, low PLT • Anemia ... Erythematosus #Diagnosis
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