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diagnosis differential hemolysis extravascular intravascular agglutinin algorithm atlas bloodcell disease disorders dyspnea morphology myelodysplasia myelodysplastic nomenclature oncology platelet rbc red
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... anemia): ... hemoglobinuria (PNH ... differential #diagnosis #hematology ... #anemia
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Warm AIHA • Cold ... • PCH • PNH ... anemia • ... #Hematology
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
- Asthma - COPD ... - Water - Pus ... Barre - ALS - Transverse ... myelitis • Hematology ... : - Anemia •
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Liver Disease, MDS ... Cell Agglutinate: Cold ... cold hemoglobinuria ... differential #diagnosis #hematology ... #microscopy #atlas
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
• Symptoms of anemia ... anemia • Cold ... IgM) • Blood smear ... disease (younger pts ... #anemia #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Autoimmune: Warm AIHA, Cold ... Liver Disease, PNH ... Defects: Sickle cell anemia ... Peripheral Blood Smear ... Differential #Diagnosis #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Infection exposure (l MD ... practices that could ... peripheral blood smear ... changes), high MCV anemia ... #Workup #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... Peripheral Smear ... Peripheral blood smear ... Syndromes #diagnosis #hematology
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