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diagnosis rheumatology differential lupus sle systemic management ra vasculitis aids arteritis autoantibodies autoimmune classification coronavirus covid19 dyspnea extraarticular extrapulmonary gca
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
- Water - Pus ... Barre - ALS - Transverse ... myelitis • Hematology ... : - Anemia • ... #pulmonary
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Malignancy (e.g. hematologic ... • May involve PNS ... neuropathy • Transverse ... lymphopenia, low PLT • Anemia ... Induced Lupus: • Symptoms
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Manifestations: - Arthritis ... - Hemolytic anemia ... autoantibodies #signs ... #symptoms #mimickers
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
of hip (rare), Arthritis ... ) Blood (75%): Anemia ... SLE #systemic #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
Extrapulmonary manifestations of COVID-19 • Neurologic: Headaches, Dizziness, Encephalopathy, Guillain-Barré, Ageusia, Myalgia, Anosmia, Stroke • Renal:
Ageusia, Myalgia, Anosmia ... vein thrombosis, Pulmonary ... Livedo reticularis, Erythematous ... Extrapulmonary #Diagnosis #Signs ... #Symptoms #SARSCOV2
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Many others • Transverse ... pain • Extra-CNS ... Systemic lupus erythematosus ... diagnosis #neurology #symptoms ... #signs
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Rheumatoid arthritis ... reticularis Blood: Anemia ... inflammation tends to cause ... pathophysiology #signs ... #symptoms #diagnosis
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Rheumatoid Arthritis ... - Signs and Symptoms ... Scleromalacia perforans • Pulmonary ... Hematological: Anemia ... #RA #Signs #Symptoms
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... ischemia • Skin: Erythematous ... • Progressive symptoms ... tract, and often causes
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... ischemia - Skin: erythematous ... systemic lupus erythematosus ... Presentation - Systemic Symptoms ... purpura: strong sign
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