19 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
leakage of RBC's secondary ... Kasabach-Merritt syndrome ... deficiencies - PNH ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Causes of Thrombocytosis ... Differential Diagnosis Secondary ... Chronic inflammatory disorders ... Myelodysplastic syndrome ... #hematology #secondary
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Nail Disorders secondary ... Muehrcke's Lines - Transverse ... • Nephrotic syndrome ... #dermatology #Differential ... Diagnosis #Algorithm #causes
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
Cardiovascular Causes ... - Water - Pus ... Hepatopulmonary syndrome ... Barre - ALS - Transverse ... myelitis • Hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Headache, Movement disorders ... , Seizure disorders ... autoantibodies that will cause ... APS), Secondary
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) - HELLP syndrome ... hemoglobinuria (PNH ... lymphoproliferative disorders ... differential #diagnosis #hematology
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
neutropenia, Kostmann syndrome ... Chediak-Higashi syndrome ... drug reactions - Secondary ... therapies-common - Secondary ... #hematology
Approach to Elevated Tryptase - Differential Diagnosis Framework

The DDx of elevated tryptase can be broken down
pass = Dangerous secondary ... Chronic & Rx-related Secondary ... Eosinophilic GI Disorders ... cell activation syndrome ... Differential #Diagnosis #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
AIHA Primary Secondary ... lymphoproliferative disorder ... Secondary Cold ... Agglutinin Syndrome ... hemolytic #anemia #hematology
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia Syndrome ... blood eosinophilia Secondary ... Causes: - Allergic ... disorders - Drug ... eosinophilia #diagnosis #hematology